许晓玉

个人基本简介

职称：教授

学位：博士

毕业院校：同济大学

电子邮件：xyxu@sdau.edu.cn

许晓玉，教授，硕士生导师，泰山学者青年专家，山东化学化工学会化学生物专业委员会委员。讲授本科生《生物化学及实验》、《制药工程专业实验B》、《无机及分析II》等课程，主要从事功能化微纳米体系的设计构建、性能表征及其在疾病早期诊断与精准治疗中的应用研究，以一作或通讯发表包括Advanced Materials, Advanced Functional Materials, Research，Advanced Drug Delivery Reviews, Journal of Materials Chemistry A, ACS Applied Materials & Interfaces, Small 等SCI论文20余篇，ESI高被引论文3篇，申请国际专利1件，授权芬兰专利1件，担任Journal of Future Foods期刊青年编委。主持国家自然科学基金青年项目，泰山人才工程及中国博士后面上项目。

主要经历

学科方向

MOFs基镧系光功能杂化材料的导向设计、构筑及检测性能研究

纳米技术助力CRISPR体系的疾病诊断和治疗研究

功能性微纳材料的设计构建及在靶向药物递送中的应用探究

荣誉获奖

2021年，上海市“超级博士后”

2019年，奥博学术大学博士后奖学金

科研项目

国家自然科学基金青年项目，2023-2025，主持

山东省泰山人才工程，2026-2029，主持

中国博士后面上项目，2021-2023，主持

山东农业大学人才引进启动项目，2024-2026, 主持

代表论著

1.Chang Liu, Xiaoyu Xu*, Droplet Microfluidics for Advanced Single-Cell Analysis, Smart Medicine, 2025; 4:e70002.

2.Shengyi Wang, Xiaoyu Xu, Tapani Viitala, Yilai Shu, and Hongbo Zhang, Unlocking mRNA-driven CRISPR-Cas9 gene therapy via optimizing mRNA and the delivery vectors, Molecular Therapy: Nucleic Acids, 2025, 36(4):102737.

3.Chang Liu, Yongyang Chen, Xiaoyu Xu, Miao Yin, Hongbo Zhang* and Wenmei Su*, Utilizing Macrophages Missile for Sulfate-Based Nanomedicine Delivery in Lung Cancer Therapy, Research, 2024, 7:0448.

4.Chang Liu, Xiaoyu Xu, Yongyang Chen, Miao Yin, Ermei Mäkilä, Wenhui Zhou, Wenmei Su*, Hongbo Zhang*, Metabolism-Regulating Nanozyme System for Advanced nanocatalytic Cancer Therapy, Small, 2024, 20(24):e2307794.

5.Xiaoyu Xu, Chang Liu, Shengyi Wang, Ermei Mäkilä, Jiali Wang, Oliver Koivisto, Junnian Zhou, Jessica M. Rosenholm, Yilai Shu* and Hongbo Zhang*, Microfluidic-assisted Biomineralization of CRISPR/Cas9 in Near-infrared Responsive Metal-organic Frameworks for Programmable Gene-editing, Nanoscale, 2022, 14, 15832-15844.

6.Xiaoyu Xu, Shengyi Wang, Yilai Shu, Hongbo Zhang*, Nanoparticle-based inner ear delivery systems for the treatment of hearing loss, Smart Materials in Medicine, 2021, 2, 350-353.

7.Xiaoyu Xu, Chang Liu, Yonghui Wang, Oliver Koivisto, Junnian Zhou, Yilai Shu, Hongbo Zhang*, Nanotechnology-based Delivery of CRISPR/Cas9 for Cancer Treatment, Advanced Drug Delivery Reviews, 2021, 176, 113891.

8.Xiaoyu Xu, Bing Yan*, An effective and simple fluorescent wearable platform for sweat Cl- analysis and logic smart-device fabrication based on color adjustable lanthanide MOFs, Journal of Materials Chemistry C, 2018, 6, 1863-1869.

9.Xiaoyu Xu, Xiao Lian, Jina Hao, Chi Zhang, Bing Yan*, Double stimuli-responsive fluorescent center for food spoilage monitoring based on dye covalent modified EuMOFs: from sensory hydrogel to logic device, Advanced Materials, 2017, 29, 1702298.

10.Xiaoyu Xu, Bing Yan*, Intelligent molecular searcher from logic computing network based on Eu(III) functionalized UMOFs for environmental monitoring, Advanced Functional Materials, 2017, 27, 1700247.

11.Xiaoyu Xu, Bing Yan*, Eu(III) functionaized ZnO@MOFs heterostructures: integration of pre-concentration and efficient charge tranfer as ppb-level sensing platform for volatile aldehyde gases in vehicles, Journal of Materials Chemistry A, 2017, 5, 2215-2223.

12.Xiaoyu Xu, Bing Yan*, Eu(III)-functionalized MIL-124 as fluorescent probe for highly selectively sensing ions and organic small molecules especially for Fe(III) and Fe(II), ACS Applied Materials & Interfaces, 2015, 7, 721-729.

发明专利

1.Encapsulated biomolecules for intracellular delivery，FI 20215856/ PCT/FI2022/050532.