Qian, Ping
Professor
Doctoral Supervisor
Education and Working Experience
2023/01 - present Professor, Shandong Agricultural University
2010/07 - 2022/12 Associate Professor, Shandong Agricultural University
2006/10 - 2010/06 Lecturer, Shandong Agricultural University
2015/02 - 2016/06 Visiting Scholar, University of Tennessee - Knoxville
2011/07 - 2014/07 Postdoc, Shandong Agricultural University
2001/09 - 2006/10 Ph.D., Liaoning Normal University
1997/09 - 2001/07 B.S., Liaoning Normal University
Research Area
Theoretical and computational chemistry
Theoretical and computational Chemical biology
Research Projects
Multiscale computer simulation of biomacromolecular systems
Establishment of force field model and molecular dynamic simulations for clay-water system
Ab initio study of clusters
Honors and Awards
2022/06 Advisor of excellent Bachelor's degree thesis of Shandong Agricultural University in 2022
2021/09 Second prize of "Teaching Quality Award" of Shandong Agricultural University
2018/09 "My favorite professional teacher" honorary title of Shandong Agricultural University
2018/06 Advisor of excellent Bachelor's degree thesis of Shandong Agricultural University in 2018
2013/09 The second teaching pioneer advanced individual of Shandong Agricultural University
2013/08 The third prize of the first micro-class teaching competition in Shandong Province
2012/09 First prize in the fourth Young Teachers' Teaching Skills Competition of Shandong Agricultural University
2011/03 "Women's achievements advanced individual" honorary title of Shandong Agricultural University
2009/12 Second prize in the first Young Teachers' Teaching Skills Competition of Shandong Agricultural University
Funding
2022/01-2025/12 the Natural Science Foundation of China (No. 22177064)
2010/01-2012/12 the Natural Science Foundation of China (No. 20903063)
2022/01-2024/12 the Natural Science Foundation of Shandong Province (No. ZR2021MB050)
2017/08-2020/06 the Natural Science Foundation of Shandong Province (No. ZR2017MB048)
Published Articles
Deng H, Ma Y, Ren WS, Vuong VQ, Qian P*, Guo H* Structure and Dynamics of the Reactive State for the Histidine Methylation Process and Catalytic Mechanism of SETD3: Insights from Quantum Mechanics/Molecular Mechanics Investigation. ACS Catalysis 2020, 10: 13314-13322.
Zhao YY, Xu XL, Deng H, Wang KN, Rahman A, Ma Y, Shaik F, Wang CM, Qian P*, Guo H* Structural and Energetic Origin of Different Product Specificities and Activities for SETD3 and Its Mutants on the Methylation of the β Actin H73K Peptide: Insights from a QM/MM Study. Journal of Chemical Theory and Computation 2023, 19: 349-362.
Ren WS, Rahman A, Jiang KB, Deng H, Zhao YY, Zhang WJ, Liu K, Qian P*, Guo H*, Unraveling the Origins of Changing Product Specificity Properties of Arginine Methyltransferase PRMT7 by the E181D and E181D/Q329A Mutations through QM/MM MD and Free-Energy Simulations. Journal of Chemical Theory and Computation 2022, 18: 2631-2641.
Ren WS, Jiang KB, Deng H, Lu N, Yu T, Guo H*, Qian P* Catalytic Mechanism and Product Specificity of Protein Arginine Methyltransferase PRMT7: A Study from QM/MM Molecular Dynamics and Free Energy Simulations. Journal of Chemical Theory and Computation 2020, 16: 5301-5312.
Qian P*, Guo HB, Wang L, Guo H* QM/MM Investigation of Substrate and Product Specificities of Suv420h2: How Does This Enzyme Generate Dimethylated H4K20 from Monomethylated Substrate? Journal of Chemical Theory and Computation 2017, 13: 2977-2986.
Hintzen JCJ, Ma H, Deng H, Witecha A, Andersen SB, Drozak J, Guo H, Qian P*, Li H*, Mecinović J* Histidine Methyltransferase SETD3 Methylates Structurally Diverse Histidine Mimics in Actin. Protein Science 2022, 31: e4305.
Al Temimi AHK, Amatdjais-Groenen HIV, Vijayendar Reddy Y, Blaauw RH, Guo H, Qian P*, Mecinović J* The Nucleophilic Amino Group of Lysine is Central for Histone Lysine Methyltransferase Catalysis. Communications Chemistry 2019, 2: 112.
Al Temimi AHK, van der Wekken-de Bruijne R, Proietti G, Guo H, Qian P*, Mecinović J* γ Thialysine versus Lysine: An Insight into the Epigenetic Methylation of Histones. Bioconjugate Chemistry 2019, 30: 1798-1804.
Yue YF, Ma Y, Qian P*, Guo H* Catalytic Mechanism of the Ubiquitin-Like NEDD8 Transfer in RING E3-E2∼NEDD8-Target Complex from QM/MM Free Energy Simulations. Journal of Chemical Information and Modeling, 2018, 58: 422-429.
Qian P*, Guo HB, Yue YF, Wang L, Yang XH, Guo H* Understanding the Catalytic Mechanism of Xanthosine Methyltransferase in Caffeine Biosynthesis from QM/MM Molecular Dynamics and Free Energy Simulations. Journal of Chemical Information and Modeling 2016, 56: 1755-1761.
Contact Information
Email: qianp@sdau.edu.cn
p: +86 156-0538-7281
Room 1110, Liberal Arts Building
No. 61 Daizong Street, Tai’an, Shandong
