工作进修经历：

2004.07-2006.06，山东农业大学，化学与材料科学学院，助教

2006.07-2012.06，山东农业大学，化学与材料科学学院，讲师

2012.07-2018.06，山东农业大学，化学与材料科学学院，副教授

2018.07至今，山东农业大学，化学与材料科学学院，教授

2013.07-2018.01，山东农业大学，生命科学学院，博士后

2016.03-2017.03，新加坡国立大学，工学院，访问学者

主要科学研究领域：

1. 新型基于光-电的生物传感器的构建及其在表观遗传修饰检测方面的应用研究。

2. 电化学传感器在食品分析和酚类污染物检测中的应用研究。

3. 抗生素、环境激素、重金属对农作物的生态毒理效应评价研究。

4. 土壤中重金属污染修复及机理研究。

主持项目：

1. 国家自然科学基金——面上项目，2018.1-2021.12，64万元。

2. 国家自然科学基金——青年项目，2012.1-2014.12，25万元。

3. 中国博士后基金一等资助，2014.7，8万元。

4. 中国博士后科学基金特别资助，2015.7，15万元。

5. 山东省自然科学基金——青年项目，2011.7-2014.7，6万元。

6. 山东省自然科学基金——面上项目，2017.1-2019.12，17万元。

7. 作物生物学国家重点实验室开放课题，2014.1-2016.12，4万元。

8. 山东农业大学杰出青年基金1项，2017.1-2020.12，60万元。

9. 山东农业大学博士后项目1项，4万元。

奖励：

1. 2011年，山东高等学校优秀科研成果奖—自然科学类二等奖，排名第二位。

2. 2011年，山东农业大学“突出贡献奖先进个人”。

3. 2012年，山东农业大学“突出贡献奖先进个人”。

4. 2013年，山东农业大学“青年岗位能手标兵”。

5. 2013年，山东高等学校优秀科研成果奖—自然科学类二等奖，排名第二位。

6. 2013年，“第十一届泰安市青年科技奖”。

7. 2015年，山东高等学校优秀科研成果奖—自然科学类三等奖，排名第一位。

8. 2015年，山东高等学校优秀科研成果奖—自然科学类三等奖，排名第二位。

9. 2016年，山东高等学校优秀科研成果奖—自然科学类二等奖，排名第一位。

10. 2016年，山东省自然科学奖三等奖，排名第二位。

11.2017年，山东省高等学校科学技术奖—自然科学类二等奖，排名第一位。

12. 2018年，山东省高等学校科学技术奖—自然科学类二等奖，排名第一位。

13. 2018年，泰安市科学技术奖——青年科技创新奖。

指导学生获得奖励情况：

1. 2012年，指导张海霞的本科毕业论文被评为“2012年山东省优秀学士学位论文”。

2. 2013年，指导王默的本科毕业论文被评为“2013年山东省优秀学士学位论文”。

3. 2017年，指导蒋积菲的本科毕业论文被评为“2017年山东省优秀学士学位论文”。

4. 2017年，指导2016届硕士研究生杨治庆的毕业论文被评为“2017年山东省优秀硕士学位论文”。

3. 2015年，指导2015届硕士研究生王默获国家奖学金。

5. 2016年，指导2016届硕士研究生杨治庆获国家奖学金。

6. 2017年，指导2017届硕士研究生李雪、李炳辰获国家奖学金。

7. 2018年，指导2018届硕士研究生王海燕、姜文静获国家奖学金。

社会兼职：

1. 中国化学会会员。

2. 《Analytical Chemistry》、《Biosensors and Bioelectronics》、《Analyst》、《Analytical ChimicaActa》、《ElectrochimicaActa》、《Sensors and Actuators B: Chemical》等期刊审稿专家。

发表的论文（*为通讯作者，†为并列一作）：

2018年

[1]Haiyan Wang, Chunling Qi, Wenhuan He, Minghui Wang, Wenjing Jiang, Huanshun Yin*, Shiyun Ai*, A sensitive photoelectrochemical immunoassay of N6-methyladenosine based on dual-signal amplification strategy: Ru doped in SiO₂nanosphere and carboxylated g-C₃N₄, Biosensors and Bioelectronics, 2018, 99, 281-288.

[2]Wenjing Jiang, Linni Wu, JunlingDuan, Huanshun Yin*, Shiyun Ai, Ultrasensitive electrochemiluminescenceimmunosensor for 5-hydroxymethylcytosine detection based on Fe₃O₄@SiO₂ nanoparticles and PAMAM dendrimers,Biosensors and Bioelectronics, 2018, 99, 660-666

[3] Minghui Wang, Yunlei Zhou, Huanshun Yin*, Wenjing Jiang, Haiyan Wang, Shiyun Ai, Signal-on electrochemiluminescence biosensor for microRNA-319a detection based on two-stage isothermal strand-displacement polymerase reaction, Biosensors and Bioelectronics 107 (2018) 34-39.

[4]Haiyan Wang, Libang Zhu, JunlingDuan, Minghui Wang, Huanshun Yin*, Po Wang*, Shiyun Ai, Photoelectrochemical biosensor for HEN1 RNA methyltransferase detection using peroxidase mimics PtCu NFs and poly(U) polymerase-mediated RNA extension, Biosensors and Bioelectronics 103 (2018) 32-38.

[5] Haiyan Wang, Huanshun Yin*, Hua Huang, Kelin Li, Yunlei Zhou, Geoffrey I.N. Waterhouse, Hai Lin*, Shiyun Ai, Dual-signal amplified photoelectrochemical biosensor for detection of N6-methyladenosine based on BiVO₄–110-TiO₂heterojunction, Ag⁺-mediated cytosine pairs, Biosensors and Bioelectronics, 108(2018) 89-96.

2017年

[1]Huanshun Yin, Zhiqing Yang, Haiyan Wang, Yunlei Zhou*, Shiyun Ai, Electrochemical biosensor for hydroxymethylated DNA detection and β-glucosyltransferase activity assay based on enzymatic catalysis triggering signal amplification, Sensors and Actuators B: Chemical, 2017, 243, 602-608.

[2]Huanshun Yin, Haiyan Wang, Wenjing Jiang, Yunlei Zhou*, Shiyun Ai*, Electrochemical immunosensor for N6-methyladenosine detection in human cell lines based on biotin-streptavidin system and silver-SiO₂ signal amplification, Biosensors and Bioelectronics, 2017, 90, 494-500.

[3]Haiyan Wang, Qihai Zhang, Huanshun Yin*, Minghui Wang, Wenjing Jiang, Shiyun Ai*, Photoelectrochemicalimmunosensor for methylated RNA detection based on g-C₃N₄/CdS quantum dots heterojunction and Phos-tag-biotin, Biosensors and Bioelectronics, 2017, 95, 124-130.

[4]Haiyan Wang, Pei Liu, Wenjing Jiang, Xue Li, Huanshun Yin*, Shiyun Ai, Photoelectrochemicalimmunosensing platform for M. SssImethyltransferase activity analysis and inhibitor screening based on g-C₃N₄ and CdS quantum dots, Sensors and Actuators B: Chemical, 2017, 244, 458-465.

[5]Xue Li, Lusheng Zhu, Yunlei Zhou, Huanshun Yin*, Shiyun Ai*, Enhanced photoelectrochemical method for sensitive detection of protein kinase A activity using TiO₂/g-C₃N₄, PAMAM dendrimer, and alkaline phosphatase, Analytical Chemistry, 2017, 89, 2369-2376.

2016年

[1]Yunlei Zhou, Huanshun Yin*, Xue Li, Zhi Li, Shiyun Ai, Hai Lin*, Electrochemical biosensor for protein kinase A activity assay based on gold nanoparticles-carbon nanospheres, phos-tag-biotin and β-galactosidase, Biosensors and Bioelectronics, 2016, 86, 508-515.

[2]Yunlei Zhou, Huanshun Yin*, Jie Li, Bingchen Li, Xue Li, Shiyun Ai, Xiansheng Zhang*, Electrochemical biosensor for microRNA detection based on poly(U) polymerase mediated isothermal signal amplification, Biosensors and Bioelectronics, 2016, 79, 79-85.

[3]Huanshun Yin, Yunlei Zhou, Bingchen Li, Xue Li, Zhiqing Yang, Shiyun Ai*, Xiansheng Zhang*, Photoelectrochemicalimmunosensor for microRNA detection based on gold nanoparticles-functionalized g-C₃N₄ and anti-DNA:RNA antibody, Sensors and Actuators B: Chemical, 2016, 222, 1119-1126.

[4]Pei Liu, Dandan Wang, Yunlei Zhou, Haiyan Wang, Huanshun Yin*, Shiyun Ai*, DNA methyltransferase detection based on digestion triggering the combination of poly adenine DNA with gold nanoparticles, Biosensors and Bioelectronics, 2016, 80, 74-78.

[5]Bingchen Li, Fei Liu, YuanyuanPeng, Yunlei Zhou, Wenxuan Fan, Huanshun Yin*, Shiyun Ai*, Xiansheng Zhang*, Two-stage cyclic enzymatic amplification method for ultrasensitive electrochemical assay of microRNA-21 in the blood serum of gastric cancer patients, Biosensors and Bioelectronics, 2016, 79, 307-312.

2015年

[1]Huanshun Yin, Xinxu Wang, YunlongGuo, Yunlei Zhou*, Shiyun Ai*, Electrochemical detection of protein kinase activity based on carboxypeptidase Y digestion triggered signal amplification, Biosensors and Bioelectronics, 2015, 66, 77-83.

[2]Huanshun Yin, Mo Wang, Bingchen Li, Zhiqing Yang, Yunlei Zhou*, Shiyun Ai*, A sensitive electrochemical biosensor for detection of protein kinase A activity and inhibitors based on Phos-tag and enzymatic signal amplification, Biosensors and Bioelectronics, 2015, 63, 26-32.

[3]Huanshun Yin, Bing Sun, Linfeng Dong, Bingchen Li, Yunlei Zhou*, Shiyun Ai, * A signal-on photoelectrochemical biosensor for assay of protein kinase activity and its inhibitor based on graphite-like carbon nitride, Phos-tag and alkaline phosphatase, Biosensors and Bioelectronics, 2015, 64, 462-468.

[4]Zhiqing Yang, Fengrui Wang, Mo Wang, Huanshun Yin*, Shiyun Ai*, A novel signal-on strategy for M.SssImethyltransfease activity analysis and inhibitor screening based on photoelectrochemicalimmunosensor, Biosensors and Bioelectronics, 2015, 66, 109-114.

[5]Zhiqing Yang, Wenjing Jiang, Fei Liu, Yunlei Zhou, Huanshun Yin*, Shiyun Ai*, A novel electrochemical immunosensor for the quantitative detection of 5-hydroxymethylcytosine in genomic DNA of breast cancer tissue, Chemical Communications, 2015, 51, 14671-14673.

2014年

[1]Yunlei Zhou, ZhenningXu, Mo Wang, Bing Sun, Huanshun Yin*, Shiyun Ai*, DNA methyltransferase activity assay based on visible light-activated photoelectrochemical biosensor, Biosensors and Bioelectronics, 2014, 53, 263-267.

[2]Huanshun Yin, Mo Wang, Yunlei Zhou, Xiaoyan Zhang, Bing Sun, Guihua Wang, Shiyun Ai*, Photoelectrochemicalbiosensing platform for microRNA detection based on in situ producing electron donor from apoferritin-encapsulated ascorbic acid, Biosensors and Bioelectronics, 2014, 53, 175-181.

[3]Huanshun Yin, Bing Sun, Yunlei Zhou, Mo Wang, ZhenningXu, Zhengliang Fu, Shiyun Ai*, A new strategy for methylated DNA detection based on photoelectrochemicalimmunosensor using Bi₂S₃nanorods, methyl bonding domain protein and anti-his tag antibody, Biosensors and Bioelectronics, 2014, 51, 103-108.

[4]Mo Wang, Huanshun Yin*, NannanShen, ZhenningXu, Bing Sun, Shiyun Ai*, Signal-on photoelectrochemical biosensor for microRNA detection based on Bi₂S₃nanorods and enzymatic amplification, Biosensors and Bioelectronics, 2014, 53, 232-237.

[5]Mo Wang, Zhengliang Fu, Bingchen Li, Yunlei Zhou, Huanshun Yin*, Shiyun Ai*, One-step, ultrasensitive and electrochemical assay of microRNAs based on T7 exonuclease assisted cyclic enzymatic amplification, Analytical Chemistry, 2014, 86, 5606-5610.

2013年

[1]Huanshun Yin†, Yunlei Zhou†, ZhenningXu, Mo Wang, Shiyun Ai*, Ultrasensitive electrochemical immunoassay for DNA methyltransferase activity and inhibitor screening based on methyl binding domain protein of MeCP2 and enzymatic signal amplification, Biosensors and Bioelectronics, 2013, 49, 39-45.

[2]Huanshun Yin†, Yunlei Zhou†, ZhenningXu, Lijian Chen, Di Zhang, Shiyun Ai*, An electrochemical assay for DNA methylation, methyltransferase activity and inhibitor screening based on methyl binding domain protein, Biosensors and Bioelectronics, 2013, 41, 492-497.

[3]Huanshun Yin, ZhenningXu, Yunlei Zhou, Mo Wang, Shiyun Ai*, An ultrasensitive electrochemical immunosensor platform with double signal amplification for indole-3-acetic acid determinations in plant seeds, Analyst, 2013, 138, 1851-1857.

[4]ZhenningXu, Mo Wang, Tingting Zhou, Huanshun Yin*, Shiyun Ai*, Electrochemical biosensing method for the detection of DNA methylation and assay of the methyltransferase activity, Sensors and Actuators B: Chemical, 2013, 178, 412-417.

2012年

[1]Yunlei Zhou, Huanshun Yin*, XiaomengMeng, ZhenningXu, Yanrong Fu, Shiyun Ai, Direct electrochemistry of sarcosine oxidase on graphene, chitosan and silver nanoparticles modified glassy carbon electrode and its biosensing for hydrogen peroxide, ElectrochimicaActa, 2012, 71, 294-301.

[2]Huanshun Yin†, Yunlei Zhou†, Haixia Zhang, XiaomengMeng, Shiyun Ai*, Electrochemical determination of microRNA-21 based on graphene, LNA integrated molecular beacon, AuNPs and biotin multifunctional bio bar codes and enzymatic assay system, Biosensors and Bioelectronics, 2012, 33, 247-253.

[3]Mo Wang, ZhenningXu, Lijian Chen, Huanshun Yin*, Shiyun Ai*, An electrochemical immunosensing platform for DNA methyltransferase activity analysis and inhibitor screening, Analytical Chemistry, 2012, 84, 9072-9078.

注：招收分析化学（生物传感）和无机化学（功能材料制备、超级电容器）方向的研究生。

通信地址：山东省泰安市岱宗大街61号山东农业大学化学与材料科学学院

邮政编码：271018

电子邮箱：yinhs@sdau.edu.cn

联系电话：0538-8247660（实验室）